Prevention of Acquisition of HIV: Preexposure Prophylaxis

The U.S. Preventive Services Task Force (USPSTF) recommends that health care providers offer pre-exposure prophylaxis (PrEP) that's approved by the U.S. Food and Drug Administration for people who are at risk of getting human immunodeficiency virus (HIV). This includes sexually active adults and adolescents who have engaged in anal or vaginal sex in the past 6 months and have any of the following:

• A sexual partner who has HIV (especially if the partner has an unknown or detectable viral load)
• A bacterial sexually transmitted infection (syphilis, gonorrhea, or chlamydia for men who have sex with men and transgender women; gonorrhea and syphilis for heterosexual women and men) in the past 6 months
• A history of inconsistent or no condom use with sex partner(s) whose HIV status is not known

It's important that people who take PrEP get counseling about medication adherence, safer sex practices including condom use, regular testing for HIV, and other necessary testing.

Per a court order, HHS is required to restore this website as of 11:59 PM, February 14, 2025. Any information on this page promoting gender ideology is extremely inaccurate, and disconnected from the immutable biological reality that there are two sexes, male and female. The Trump Administration rejects gender ideology and condemns the harms it causes to children, by promoting their chemical and surgical mutilation, and to women, by depriving them of their dignity, safety, well-being, and opportunities. This page does not reflect biological reality and therefore the Administration and this Department rejects it.